ER Retention of Soluble Proteins: Retrieval, Retention, or Both?
نویسندگان
چکیده
منابع مشابه
Polybasic Trafficking Signal Mediates Golgi Export, ER Retention or ER Export and Retrieval Based on Membrane-Proximity
Trafficking of integral membrane proteins between the ER and Golgi complex, and protein sorting and trafficking between the TGN and endosomal/lysosomal compartments or plasma membranes, are dependent on cis-acting, linear amino acid sorting signals. Numerous sorting signals of this type have been identified in the cytoplasmic domains of membrane proteins, several of which rely on basic residues...
متن کاملYos9p and Hrd1p mediate ER retention of misfolded proteins for ER-associated degradation
The endoplasmic reticulum (ER) has an elaborate quality control system, which retains misfolded proteins and targets them to ER-associated protein degradation (ERAD). To analyze sorting between ER retention and ER exit to the secretory pathway, we constructed fusion proteins containing both folded carboxypeptidase Y (CPY) and misfolded mutant CPY (CPY*) units. Although the luminal Hsp70 chapero...
متن کاملBloating or water retention?
Whether you're experiencing abdominal bloating, excess gas, or the burping blues, there are many possible causes of your discomfort. Water retention, also known as edema, is an accumulation of extra fluid that?s commonly caused by a temporary imbalance in your electrolyte [2] and fluid levels. While you're right that a diet high in sodium may lead to bloating, it's not the only cause. It could ...
متن کاملBloating or water retention?
Whether you're experiencing abdominal bloating, excess gas, or the burping blues, there are many possible causes of your discomfort. Water retention, also known as edema, is an accumulation of extra fluid that?s commonly caused by a temporary imbalance in your electrolyte [2] and fluid levels. While you're right that a diet high in sodium may lead to bloating, it's not the only cause. It could ...
متن کاملBloating or water retention?
Whether you're experiencing abdominal bloating, excess gas, or the burping blues, there are many possible causes of your discomfort. Water retention, also known as edema, is an accumulation of extra fluid that?s commonly caused by a temporary imbalance in your electrolyte [2] and fluid levels. While you're right that a diet high in sodium may lead to bloating, it's not the only cause. It could ...
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ژورنال
عنوان ژورنال: The Plant Cell
سال: 2000
ISSN: 1040-4651,1532-298X
DOI: 10.1105/tpc.12.9.1517